Summary: Drug interactions are reported among people who take Lisinopril and Pomegranate together. You've previously warned that pomegranate juice could interfere with certain prescription drugs. They are cranberry, gogi, mangosteen, noni, acai, pomegranate, and sea buckthorn. In the 15 years since the discovery that grapefruit juice inhibits cytochrome P-450 3A4 (CYP3A4) in the wall of the small intestine, much work has been done to further define interactions with grapefruit juice and, more recently, with other fruit juices. Pomegranate may interfere with medications like Carbamazepine (Tegretol), Rosuvastatin (Crestor), Warfarin (Coumadin), and Tolbutamide (Orinase). Pomegranate juice is LIKELY SAFE ffor most people when taken by mouth. Are There Pomegranate Juice Interactions with Statins? Pomegranate juice is full of antioxidants and other nutrients that are associated with several wellness advantages. If you are taking prescription medication and plan on supplementing with pomegranate extract, speak to a doctor and ask about any possible drug interactions. It depends on what you’re taking the supplement for. About Pomegranates and Hypertension. What about pomegranate juice interactions? This review analyzes the effectiveness and drug interactions between Cozaar and Pomegranate. Pomegranate juice does not interact with drugs as strongly as grapefruit juice but there is a risk. You are taking metformin: In an animal study, pomegranate juice reduced the effectiveness of metformin. Pomegranate juice is highly concentrated with … Additional grapefruit juice drug interactions, and interactions with other juices, can be researched in the Drug Interaction Checker. Cholesterol drugs that grapefruit effects includes: atorvastatin (Lipitor), lovastatin (Mevacor), simvastatin (Zocor). —R.M.H., Durham, N.C. Several. You are taking warfarin: Pomegranate juice may interact with warfarin. I take Lipitor and wonder if I should be concerned. Pomegranate is an exotic fruit with medicinal properties and substances that interfere with medications. What medication does pomegranate interfere with? Learn more about Pomegranate uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Pomegranate Prescription medications are generally safe and effective, but many of them can interact poorly with certain foods. Possible fruit, juice and supplement interactions with commonly prescribed drugs 2, 3 Pomegranate fruit extract is a rich source of polyphenols, chemicals in plants that provide their flavor and color. Pomegranates, for instance, can lower blood pressure, and if you combine them with a blood pressure medication, it may cause extremely low blood pressure. Most people do not experience side effects.Some people can have allergic reactions to pomegranate fruit. Blood pressure medications are one example of drugs that can be affected by the food you eat. Pomegranates, particularly when juiced, may improve your health and reduce your risk of cardiovascular disease, cancer and osteoarthritis. More information below and also, check with your doctor. Table 1. The skin should feel firm and it should have a bright red to deep red color with leathery skin. As with previous reports of interactions between food and warfarin, this case does not definitively prove the association between pomegranate … Which medicines are affected by these interactions and how should patients be advised? The table below lists some of the better established interactions with medicines, it is not a complete list. Which medicines are affected by these interactions and how should patients be advised? Grapefruit interferes with the breakdown of drug causing a higher level of drug in the body. However, it isn't recommended for people on certain medications, as it can cause some unanticipated interactions. The table below lists some of the better established interactions with medicines, it is not a complete list. It is created by eHealthMe based on reports of 3 people who take the same drugs from Food and Drug Administration (FDA), and is updated regularly. Aug. 19, 2008 -- Grapefruit, orange, and apple juices block drugs commonly used to treat infections, allergy, transplant rejection, cancer, and high blood pressure. This study is created by eHealthMe based on reports of 19 people who take Lisinopril and Pomegranate from Food and Drug Administration (FDA), and is updated regularly. Pomegranates are one of the few fruits where the juice is just as beneficial as the fruit or seeds. If you’re planning on taking pomegranate extract, you may wonder what dose you should take.